Chronic lung disease & air travel
When an aircraft is cruising, cabin air has a partial oxygen pressure that is approximately 20-25% less than at sea level. This presents no problem to healthy people who, when breathing cabin air, will have an arterial oxygen (PaO2) of approximately 70 mmHg and haemoglobin saturation of 90%. However, in some medical conditions this may be sufficient to produce tissue hypoxia. The patient's exercise tolerance provides a guide to their fitness to fly. Dyspnoea at rest is generally a contraindication. If a person can climb a flight of 15 stairs and walk 50 - 100 metres without symptoms they should not experience problems during the flight. People with poor exercise tolerance need further assessment preferably in consultation with a respiratory physician. Further assessment involves respiratory function tests and measurement of arterial blood gases. If PaO2 is more than 70 mmHg then supplementary oxygen is not needed. The arterial carbon dioxide (PaCO2) is also important as supplemental oxygen may reduce respiratory drive in hypercapneic patients. People with lung disease should avoid alcohol during the flight as this may worsen hypoxia.